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a Protein–protein interaction (PPI) networks of 9 target proteins associated with late relapse shown in red were analyzed by STRING database with a confidence score of 0.4, and five more targets were identified and shown in yellow. Line thickness indicates the strength of data support. b Top 15 pathways from <t>KEGG</t> pathway analysis of 9 proteins associated with late relapse. X-axis indicates the significance (–log 10 [FDR]) of the pathway association, in bars. The PPI image was created using Cytoscape (ver. 3.9.1, https://cytoscape.org ). The image of pathway analysis was created <t>using</t> <t>GraphPad</t> Prism 9 ( www.graphpad.com ).
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Image Search Results


a Protein–protein interaction (PPI) networks of 9 target proteins associated with late relapse shown in red were analyzed by STRING database with a confidence score of 0.4, and five more targets were identified and shown in yellow. Line thickness indicates the strength of data support. b Top 15 pathways from KEGG pathway analysis of 9 proteins associated with late relapse. X-axis indicates the significance (–log 10 [FDR]) of the pathway association, in bars. The PPI image was created using Cytoscape (ver. 3.9.1, https://cytoscape.org ). The image of pathway analysis was created using GraphPad Prism 9 ( www.graphpad.com ).

Journal: PLOS ONE

Article Title: Biomarker combination predicting imminent relapse after discontinuation of biological drugs in patients with rheumatoid arthritis in remission

doi: 10.1371/journal.pone.0299450

Figure Lengend Snippet: a Protein–protein interaction (PPI) networks of 9 target proteins associated with late relapse shown in red were analyzed by STRING database with a confidence score of 0.4, and five more targets were identified and shown in yellow. Line thickness indicates the strength of data support. b Top 15 pathways from KEGG pathway analysis of 9 proteins associated with late relapse. X-axis indicates the significance (–log 10 [FDR]) of the pathway association, in bars. The PPI image was created using Cytoscape (ver. 3.9.1, https://cytoscape.org ). The image of pathway analysis was created using GraphPad Prism 9 ( www.graphpad.com ).

Article Snippet: The STRING functional enrichment outputs on the KEGG pathway were created using GraphPad Prism 9.

Techniques: